Therefore, pterostilbene is a better alternative. However, resveratrol is difficult to be absorbed by the gut, and the little resveratrol that ends up in the body is broken down very quickly. Resveratrol is needed to activate the sirtuin genes (which protect our DNA and epigenome), while NMN is needed to fuel the sirtuins. Studies have shown that resveratrol can reduce the risk of heart disease, cancer, and neurodegeneration.ĭavid Sinclair believes that resveratrol works synergistically with NMN. Resveratrol is a stilbenoid found in the skin of grapes in low amounts. Our view: We are lukewarm about resveratrol. TMG (trimethylglycine or betaine): 500 mg to 1,000 mg per dayĢ.
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